However, Jacobs told Fancast that House will include a storyline explaining Thirteen's departure and eventual return.
"It's linked to narrative," she said. "When Thirteen does come back, it's not like she's just going to be sitting in the office doing a diagnosis. There's a real reason why she had to leave - it's surprising and juicy and it deepens her character and our understanding of her."
source: DigitalSpy